{"id":281,"date":"2026-01-29T15:08:17","date_gmt":"2026-01-29T15:08:17","guid":{"rendered":"https:\/\/pharmacykit.in\/?p=281"},"modified":"2026-01-29T15:11:58","modified_gmt":"2026-01-29T15:11:58","slug":"mcq-pharmacology","status":"publish","type":"post","link":"https:\/\/pharmacykit.in\/?p=281","title":{"rendered":"MCQ 01-10 &#8211; PHARMACOLOGY"},"content":{"rendered":"\n<ol class=\"wp-block-list\">\n<li>Which of the following is a broad-spectrum antibiotic?<br \/>A. Penicillin G<br \/>B. Amoxicillin<br \/>C. Erythromycin<br \/>D. Chloramphenicol<\/li>\n<\/ol>\n\n\n\n<p>\u2705 Answer: D. Chloramphenicol<br \/>\ud83d\udca1 Explanation: Chloramphenicol acts on both Gram-positive and Gram-negative bacteria.<\/p>\n\n\n\n<ol start=\"2\" class=\"wp-block-list\">\n<li>The mechanism of action of penicillin is:<br \/>A. Inhibition of protein synthesis<br \/>B. Inhibition of nucleic acid synthesis<br \/>C. Inhibition of cell wall synthesis<br \/>D. Disruption of cell membrane<\/li>\n<\/ol>\n\n\n\n<p>\u2705 Answer: C. Inhibition of cell wall synthesis<br \/>\ud83d\udca1 Explanation: Penicillin inhibits peptidoglycan synthesis in bacterial cell walls.<\/p>\n\n\n\n<ol start=\"3\" class=\"wp-block-list\">\n<li>Tetracyclines act by inhibiting:<br \/>A. RNA polymerase<br \/>B. 30S ribosomal subunit<br \/>C. 50S ribosomal subunit<br \/>D. DNA gyrase<\/li>\n<\/ol>\n\n\n\n<p>\u2705 Answer: B. 30S ribosomal subunit<br \/>\ud83d\udca1 Explanation: Tetracyclines block aminoacyl-tRNA binding to the ribosome, preventing protein synthesis.<\/p>\n\n\n\n<ol start=\"4\" class=\"wp-block-list\">\n<li>Which of the following antibiotics is ototoxic and nephrotoxic?<br \/>A. Streptomycin<br \/>B. Ampicillin<br \/>C. Azithromycin<br \/>D. Chloramphenicol<\/li>\n<\/ol>\n\n\n\n<p>\u2705 Answer: A. Streptomycin<br \/>\ud83d\udca1 Explanation: Streptomycin (an aminoglycoside) can damage the ear (ototoxicity) and kidneys (nephrotoxicity).<\/p>\n\n\n\n<ol start=\"5\" class=\"wp-block-list\">\n<li>Vancomycin is mainly used against:<br \/>A. Gram-negative bacteria<br \/>B. Gram-positive bacteria<br \/>C. Fungi<br \/>D. Viruses<\/li>\n<\/ol>\n\n\n\n<p>\u2705 Answer: B. Gram-positive bacteria<br \/>\ud83d\udca1 Explanation: Vancomycin is effective against resistant Gram-positive organisms like MRSA.<\/p>\n\n\n\n<ol start=\"6\" class=\"wp-block-list\">\n<li>Which antibiotic inhibits DNA gyrase?<br \/>A. Erythromycin<br \/>B. Ciprofloxacin<br \/>C. Doxycycline<br \/>D. Linezolid<\/li>\n<\/ol>\n\n\n\n<p>\u2705 Answer: B. Ciprofloxacin<br \/>\ud83d\udca1 Explanation: Fluoroquinolones like ciprofloxacin inhibit bacterial DNA gyrase and topoisomerase IV.<\/p>\n\n\n\n<ol start=\"7\" class=\"wp-block-list\">\n<li>Sulfonamides act by inhibiting:<br \/>A. Folic acid synthesis<br \/>B. Cell wall synthesis<br \/>C. Protein synthesis<br \/>D. DNA replication<\/li>\n<\/ol>\n\n\n\n<p>\u2705 Answer: A. Folic acid synthesis<br \/>\ud83d\udca1 Explanation: Sulfonamides are structural analogs of PABA and inhibit dihydropteroate synthase.<\/p>\n\n\n\n<ol start=\"8\" class=\"wp-block-list\">\n<li>Which antibiotic causes gray baby syndrome?<br \/>A. Gentamicin<br \/>B. Chloramphenicol<br \/>C. Tetracycline<br \/>D. Erythromycin<\/li>\n<\/ol>\n\n\n\n<p>\u2705 Answer: B. Chloramphenicol<br \/>\ud83d\udca1 Explanation: Due to immature liver enzymes in neonates, chloramphenicol accumulates and causes toxicity.<\/p>\n\n\n\n<ol start=\"9\" class=\"wp-block-list\">\n<li>The antibiotic erythromycin belongs to which class?<br \/>A. Aminoglycoside<br \/>B. Macrolide<br \/>C. Beta-lactam<br \/>D. Quinolone<\/li>\n<\/ol>\n\n\n\n<p>\u2705 Answer: B. Macrolide<br \/>\ud83d\udca1 Explanation: Erythromycin is a macrolide that inhibits protein synthesis by binding to the 50S ribosomal subunit.<\/p>\n\n\n\n<ol start=\"10\" class=\"wp-block-list\">\n<li>Metronidazole is mainly effective against:<br \/>A. Gram-positive bacteria<br \/>B. Gram-negative bacteria<br \/>C. Anaerobic bacteria and protozoa<br \/>D. Viruses<\/li>\n<\/ol>\n\n\n\n<p>\u2705 Answer: C. Anaerobic bacteria and protozoa<br \/>\ud83d\udca1 Explanation: Metronidazole damages DNA of anaerobic organisms and protozoa like Giardia and Entamoeba.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#46;&#46;&#46;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[53],"tags":[55,54],"_links":{"self":[{"href":"https:\/\/pharmacykit.in\/index.php?rest_route=\/wp\/v2\/posts\/281"}],"collection":[{"href":"https:\/\/pharmacykit.in\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmacykit.in\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmacykit.in\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmacykit.in\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=281"}],"version-history":[{"count":4,"href":"https:\/\/pharmacykit.in\/index.php?rest_route=\/wp\/v2\/posts\/281\/revisions"}],"predecessor-version":[{"id":289,"href":"https:\/\/pharmacykit.in\/index.php?rest_route=\/wp\/v2\/posts\/281\/revisions\/289"}],"wp:attachment":[{"href":"https:\/\/pharmacykit.in\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=281"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmacykit.in\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=281"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmacykit.in\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=281"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}